This one is tough. Our family was close until our son got married.?

Our son got married three years ago. No matter what we do or say it is always the wrong thing. We make our daughter in law upset or mad. Since he got married we have not had one family gathering on his side that hasn't ended with her being mad or offended. I know he doesn't treat her family this way. I did find out that she grew up with her mom not getting along with her dad's folks. I have tried everything I know of and have really reached my end. We have never had anyone treat us so rudely or unkindly, not to mention the spot she put her husband, our son in. Any advice?